Beilstein J. Org. Chem.2024,20, 460–469, doi:10.3762/bjoc.20.41
generate a fluoride ion that facilitates limiting enolization processes, and an electrophilic N–Ffluorinatingagent that is reactive towards neutral enol species.
Keywords: difluorination; difluoromethylene; direct fluorination; electrophilic fluorination; organofluorine; Introduction
Fluorine is
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Graphical Abstract
Scheme 1:
Monofluorination of 1,3-diphenylpropane-1,3-dione with Selectfluor.
Beilstein J. Org. Chem.2021,17, 1752–1813, doi:10.3762/bjoc.17.123
and reactions of these reagents are described chronologically and the review also discusses the relative fluorination power of each reagent and their mechanisms chronicling developments from a historical perspective.
Keywords: N-Ffluorinatingagent; fluorination; fluorodiazoniabicyclo[2.2.2]octane